Clinical and diagnostic value of alcohol biomarkers

Alcohol abuse is a socially significant problem that makes negative contribution to the world health statistics. one of main factors mortality in Russia. Despite current situation, existing diagnostic approaches patients with possible alcohol and alcohol-associated diseases do not always allow us determine direct severity prognosis course these diseases. Objective tools for identifying monitoring fact consumption its pattern clinical practice can be useful from point view managing patient’s disease. In addition, informing about possibilities such diagnosis motivate them refuse take during further treatment, thereby improving Currently, various have been developed assess nature consumption, including determination ethanol blood, but all found their wide application practice. this review, we presented information biomarkers currently developed: alanine aminotransferase, aspartate gamma-glutamyltranspeptidase, mean corpuscular volume, carbohydrate-deficient transferrin, ethylglucuronide ethylsulfate, phosphatidylethanol, ethyl esters fatty acids, described disadvantages advantages terms high sensitivity specificity some biomarkers, example, results laboratory assessment content should interpreted only context relevant factors, presentation, medical history, mental physical patient